After guiding Pakistan to a much-needed win over Sri Lanka in the final Group B match of the ICC Champions Trophy on Monday, skipper Sarfraz Ahmed had faced an awkward situation just before the post-match press conference at Cardiff.
While chasing, Pakistan cruised to complete the target in 37.1 overs, after openers Azhar Ali and Fakhar Zaman provided a flawless start. Azhar's first sign of aggression came in the 13th over when he struck a six and a four and soon caught up with Zaman, who completed a 49 ball 50.
Their opposite number Bairstow - brought in to open for the first time in worldwide cricket in place of the out-of-form Jason Roy - had responded with a battling 43, but on a used pitch that precluded fluent strokeplay as the ball swung too, England could never get a foothold and folded tamely in their attempt to set a defendable total.
They will be up against a Pakistan side in good form and full of confidence from their wins over South Africa and Sri Lanka.
Zaman's catch brought curtains to Ali's innings and gave England their sixth jolt.
Bairstow replaced Roy after the Surrey opener had managed just 51 runs in eight one-day global innings so far this season.
Pakistan bowled and fielded tightly to restrict the sluggish hosts who failed to master a lifeless wicket and collapsed from 128 for two in bright and sunny conditions which normally favour batsmen. Ben Stokes, so dominant against Australia last week, ended up becalmed, his 34 taking 64 balls and containing not a single boundary.
Yet Bairstow, opening for the first time in ODI cricket, had a narrow escape second ball when still on nought, after Junaid Khan appealed for lbw but he was given not out and Pakistan's review was unsuccessful.
Medium-fast Rumman Raees took 2-44 off nine overs on an impressive ODI debut, being called up late to replace Mohammad Amir, who had a back spasm.
England's captain, Eoin Morgan, did not sound unduly concerned about the surface.
He eventually holed out to cover when deceived by Hasan's slower ball.
He said: "One of the huge contributing factors towards topping our table and playing very good cricket in the group stages is that we've stayed true to what we believe in and what's worked for us the last couple of years, and I think that's the continued formula for the future".