Some parts of Northeast Ohio could see over a foot of snow. The weather service said accumulation will be most persistent Sunday afternoon.
A clipper system is set to move through late Monday night and Tuesday to bring a minor to moderate accumulating snow for all.
East of Lake Ontario, with its broader fetch and more favorable wind direction, higher accumulations are in the cards.
Snow flurries will cross the region again this evening and overnight as another weak disturbance pushes through the area.
A few inches are possible in the snowbelt just south of Lake Erie.
Snow should ease in Buffalo and the Niagara Frontier after lunch Tuesday as winds shift out of the north. Locally, more than 6 inches of snow fell due to the lake effect.
Temperatures dipping into the teens and snow ranging from an inch to 5 inches are predicted for the Youngstown area beginning Monday night through Tuesday, according to the National Weather Service's Cleveland office. Erie, Pennsylvania, and southwestern NY, as well as spots south of Lake Ontario, including Rochester and Syracuse, are where model guidance is dumping the heaviest accumulations.
By Thursday morning, this new system will move into the mid-Atlantic states and could bring some snow from West Virginia to Maryland and into Pennsylvania, New Jersey and maybe even New York City and Long Island.
In addition to the snow, the coldest air of the season is forecast Tuesday in the Great Lakes from Chicago to Detroit.