France have won four of the last five Six Nations meetings between the two, however, Scotland will be looking to make home advantage count.
Sportsmail's GLEN WILLIAMS will be bringing you all the live action with updates from RORY KEANE at Murrayfield.
"We felt like we were testing them and knew if we held onto the ball, we would cause them trouble".
"It's felt like a long time coming back from injury and I'm not a very good watcher, as my wife will tell you, so it's great to get back on this field, in this jersey and in front of this crowd".
The tenure of Jacques Brunel is in its infancy and his side must prove to all that they can deliver away from home in this Championship.
Scotland were outshone by Wales in Cardiff and France lost in the final kick of the game as Johnny Sexton slotted a glorious drop goal through the posts to give Ireland a narrow victory.
Scotland had the momentum and took the lead with ten minutes to go as the French exhausted, scoring again thanks to Laidlaw's reliable right boot.
Sometimes he can force plays and if he can manage the game better, he should be able to find the right time to launch Scotland's unsafe runners.
"All the carriers in the team did well - Huw Jones getting on the ball, Stuart Hogg outside, Peter Horne worked really hard".
The hosts then pressed on, converting two more penalty kicks and securing their first win in this year's Six Nations. The winger touched down after just two minutes thanks to a brilliant solo run.
"It was a brutally physical game against them previous year, there were a lot of collisions". France's kicks, by contrast, were far more risky, as Thomas proved with his second try after 26 minutes. The pressure started to toll on France and their errors mounted up. "The forwards had such a massive game in the set-piece, but they were still willing carriers right to the end".
"If you lose the first match and are serious about the competition, the maths is simple", Scotland captain John Barclay said.
Scrum-half Ali Price - whose intercepted pass handed Wales' Gareth Davies the crucial opening score in Cardiff - is joined on the bench by last week's starters Jon Welsh, Ben Toolis and Chris Harris.
France: Geoffrey Palis; Teddy Thomas, Rémi Lamerat, Geoffrey Doumayrou, Virimi Vakatawa; Lionel Beauxis, Maxime Machenaud; Jefferson Poirot, Guilhem Guirado (captain), Rabah Slimani, Arthur Iturria, Sébastien Vahaamahina, Wenceslas Lauret, Yacouba Camara, Marco Tauleigne.
Replacements: 16 Adrien Pelissie, 17 Eddy Ben Arous, 18 Cedate Gomes Sa, 19 Paul Gabrillagues, 20 Louis Picamoles, 21 Baptiste Serin, 22 Anthony Belleau, 23 Benjamin Fall.
The BBC Sport website will also be showing live coverage of the game, with live text commentary available too.