The Premier League fixtures for the 2018-19 season were published on Thursday and the Arsenal-Man City game was the standout on the opening weekend.
Jose Mourinho's side will be facing Tottenham Hotspur in the opening month at home and have games against mid-table sides ahead of their first tough away trip to Chelsea in October.
Liverpool's pre-Europe travels The Premier League has released dates for all 380 matches, but none have been allotted kick-off times as broadcasters are yet to decide which games will be televised.
Securing their second fourth-place finish in succession was still a cause for some celebration, and it means they will enjoy back-to-back seasons in the UEFA Champions League for the first time since 2009-10.
Fulham, who booked their place in the top flight with victory over Aston Villa in the Championship play-off final, begin at home to Crystal Palace, before the trip to Spurs is followed by Burnley at home and Brighton away.
During their impressive march to the UEFA Champions League final in 2017-18, it went slightly unnoticed that Liverpool only narrowly finished in the top four in the Premier League.
Olivier Giroud will play former club Arsenal for the first time since moving to Chelsea.
With the last two meetings between English football's two biggest clubs at Anfield ending in dismal 0-0 draws, it is to be hoped that December's clash on Merseyside produces more drama and goals.
It is a similar story for neighbours United, who begin at home to Leicester.
Spurs will use Wembley Stadium for their first home game of the season, against Fulham, and will also play three away games before they officially open their new facility against Liverpool on September 15th.